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Assay Detail

CHEMBL1000234

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at PPARalpha receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Peroxisome proliferator-activated receptor alpha (CHEMBL239)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

An innovative method to study target protein-drug interactions by mass spectrometry.
Müller MQ, de Koning LJ, Schmidt A, Ihling C, Syha Y, Rau O, Mechtler K, Schubert-Zsilavecz M, Sinz A.
J Med Chem (2009) 52 : 2875 -2879
PubMed 19379014 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.16 5.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL491950 1 5.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL491950 EC50 = 7000.0 nM 5.16