Assay Detail
Binding
CHEMBL1000423
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE3 in human platelet
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Recent advances on phosphodiesterase 4 inhibitors for the treatment of asthma and chronic obstructive pulmonary disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.87 | 7.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL453855 | — | — | 1 | 7.50 |
| CHEMBL313842 | ZARDAVERINE | 2.0 | 1 | 6.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL453855 | — | IC50 | = | 31.62 | nM | 7.50 |
| CHEMBL313842 | ZARDAVERINE | IC50 | = | 575.44 | nM | 6.24 |