Assay Detail
Functional
CHEMBL1000746
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Antitumor activity against human COLO205 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | COLO 205 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Comparison of fascaplysin and related alkaloids: a study of structures, cytotoxicities, and sources.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.00 | 6.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL446125 | FASCAPLYSIN A | — | 1 | 6.08 |
| CHEMBL258765 | FASCAPLYSIN CHLORIDE | — | 1 | 5.92 |
| CHEMBL470052 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL446125 | FASCAPLYSIN A | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL258765 | FASCAPLYSIN CHLORIDE | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL470052 | — | IC50 | > | 10000.0 | nM | - |