Assay Detail
Functional
CHEMBL1001108
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MIAPaCa2 cells after 48 hrs by alamar blue assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MIA PaCa-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of novel stilbene-based antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 7.04 | 8.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 8.10 |
| CHEMBL90555 | VINCRISTINE | 4.0 | 1 | 7.82 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 7.60 |
| CHEMBL490294 | — | — | 1 | 7.40 |
| CHEMBL524493 | — | — | 1 | 7.10 |
| CHEMBL502199 | — | — | 1 | 6.75 |
| CHEMBL490295 | — | — | 1 | 6.70 |
| CHEMBL491277 | — | — | 1 | 6.70 |
| CHEMBL454401 | — | — | 1 | 6.16 |
| CHEMBL521616 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL90555 | VINCRISTINE | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL107 | COLCHICINE | IC50 | = | 25.0 | nM | 7.60 |
| CHEMBL490294 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL524493 | — | IC50 | = | 80.0 | nM | 7.10 |
| CHEMBL502199 | — | IC50 | = | 180.0 | nM | 6.75 |
| CHEMBL490295 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL491277 | — | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL454401 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL521616 | — | IC50 | = | 800.0 | nM | 6.10 |