Assay Detail
Binding
CHEMBL1002075
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human carbonic anhydrase 2 esterase activity by uncompetitive Lineweaver-Burke plot
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
In vitro inhibition of salicylic acid derivatives on human cytosolic carbonic anhydrase isozymes I and II.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.90 | 5.90 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1375 | 5-CHLOROSALICYLIC ACID | — | 1 | 5.90 |
| CHEMBL448399 | HYDROXYTOLUIC ACID | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1375 | 5-CHLOROSALICYLIC ACID | Ki | = | 1270.0 | nM | 5.90 |
| CHEMBL448399 | HYDROXYTOLUIC ACID | Ki | = | 10570000.0 | nM | - |