Assay Detail
Functional
CHEMBL1003191
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Anesthetic potency in Rana temporaria tadpoles assessed as loss of righting reflex for 60 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rana temporaria |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Identification of anesthetic binding sites on human serum albumin using a novel etomidate photolabel.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 4.70 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL681 | ETOMIDATE | 4.0 | 1 | 4.96 |
| CHEMBL279678 | S-ETOMIDATE | -1.0 | 1 | 4.44 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL681 | ETOMIDATE | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL279678 | S-ETOMIDATE | EC50 | = | 36000.0 | nM | 4.44 |