Assay Detail
Functional
CHEMBL1005023
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at rat P2Y6 receptor expressed in human 1321N1 cells assessed as increase in intracellular calcium concentration by dual-excitation spectrofluorimetric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | 1321-N1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of hydrolytically stable and selective P2Y(1) receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.70 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL130266 | URIDINE_DIPHOSPHATE | — | 1 | 6.70 |
| CHEMBL2448400 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL130266 | URIDINE_DIPHOSPHATE | EC50 | = | 200.0 | nM | 6.70 |
| CHEMBL2448400 | — | EC50 | - | — | - |