Assay Detail
Binding
CHEMBL1005437
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Inhibition of MMP10
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Specific targeting of metzincin family members with small-molecule inhibitors: progress toward a multifarious challenge.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.78 | 5.78 |
| IC50 | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495502 | — | — | 1 | 5.78 |
| CHEMBL402393 | — | — | 1 | - |
| CHEMBL253275 | — | — | 1 | - |
| CHEMBL325163 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495502 | — | Ki | = | 1650.0 | nM | 5.78 |
| CHEMBL402393 | — | Ki | > | 5346.0 | nM | - |
| CHEMBL253275 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL325163 | — | Ki | > | 2000.0 | nM | - |