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Assay Detail

CHEMBL1006074

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of xanthine oxidase
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Xanthine dehydrogenase/oxidase (CHEMBL1929)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Structural revision of aspernigrin A, reisolated from Cladosporium herbarum IFB-E002.
Ye YH, Zhu HL, Song YC, Liu JY, Tan RX.
J Nat Prod (2005) 68 : 1106 -1108
PubMed 16038560 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.75 4.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL469613 RUBROFUSARIN B 1 4.78
CHEMBL451678 FONSECINONE A 1 4.71

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL469613 RUBROFUSARIN B IC50 = 16800.0 nM 4.78
CHEMBL451678 FONSECINONE A IC50 = 19500.0 nM 4.71