Assay Detail

CHEMBL1006910

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Inhibition of protein farnesyltransferase

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.

Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-Sánchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM.
J Nat Prod (2002) 65 : 842 -850
PubMed 12088425 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.66	5.66

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL512065	OCHRACEOLIDE A	—	1	5.66

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL512065	OCHRACEOLIDE A	IC50	=	2200.0	nM	5.66