Assay Detail
Binding
CHEMBL1006960
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant His-tagged HAT p300 expressed in Sf21-Baculovirus system
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Synthesis of isothiazol-3-one derivatives as inhibitors of histone acetyltransferases (HATs).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL455368 | ANACARDIC ACID | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL455368 | ANACARDIC ACID | IC50 | = | 5000.0 | nM | 5.30 |