Assay Detail
Binding
CHEMBL1007461
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Binding affinity to Escherichia coli 23S rRNA L11 binding domain
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Design and implementation of an ribonucleic acid (RNA) directed fragment library.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 6.50 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507798 | MICROCOCCIN | — | 1 | 7.10 |
| CHEMBL1236460 | THIOSTREPTON | — | 1 | 5.89 |
| CHEMBL2103750 | NOSIHEPTIDE | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507798 | MICROCOCCIN | Kd | = | 80.0 | nM | 7.10 |
| CHEMBL1236460 | THIOSTREPTON | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL2103750 | NOSIHEPTIDE | Kd | < | 3000.0 | nM | - |