Assay Detail
Binding
CHEMBL1007656
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from 5HT2A receptor in rabbit cerebral cortex membrane
4
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Oryctolagus cuniculus |
| Tissue | Cerebral cortex |
| Subcellular | Membrane |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Activity of Parthenolide at 5HT2A receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 8.16 | 8.24 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1065 | METHYSERGIDE | 4.0 | 1 | 8.24 |
| CHEMBL12314 | MESULERGINE | 2.0 | 1 | 8.08 |
| CHEMBL4298697 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1065 | METHYSERGIDE | Ki | = | 5.7 | nM | 8.24 |
| CHEMBL12314 | MESULERGINE | Ki | = | 8.3 | nM | 8.08 |
| CHEMBL4298697 | — | Ki | = | 230000.0 | nM | - |
| CHEMBL4298697 | — | Activity | - | — | - |