Assay Detail
Binding
CHEMBL1008388
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Inhibition of CAMK2
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-alpha production in human whole blood.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.57 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL495617 | — | — | 1 | 5.58 |
| CHEMBL527026 | — | — | 1 | 4.41 |
| CHEMBL501709 | — | — | 1 | 4.16 |
| CHEMBL523059 | — | — | 1 | 4.12 |
| CHEMBL230232 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL495617 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL527026 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL501709 | — | IC50 | = | 70000.0 | nM | 4.16 |
| CHEMBL523059 | — | IC50 | = | 75000.0 | nM | 4.12 |
| CHEMBL230232 | — | IC50 | > | 100000.0 | nM | - |