Assay Detail
Functional
CHEMBL1008720
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Cytotoxicity against human HeLa cells by SRB assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antitubercular sesterterpenes from the Thai sponge Brachiaster sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.77 | 6.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL514498 | HETERONEMIN | — | 1 | 6.35 |
| CHEMBL490765 | — | — | 1 | 5.78 |
| CHEMBL250263 | — | — | 1 | 5.70 |
| CHEMBL490567 | — | — | 1 | 5.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL514498 | HETERONEMIN | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL490765 | — | IC50 | = | 1680.0 | nM | 5.78 |
| CHEMBL250263 | — | IC50 | = | 1990.0 | nM | 5.70 |
| CHEMBL490567 | — | IC50 | = | 5490.0 | nM | 5.26 |