Assay Detail
Binding
CHEMBL1009437
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of G-quadruplex-induced human TERT in H1299 cells by TRAP assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | H1299 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.13 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL144757 | — | — | 1 | 5.17 |
| CHEMBL89250 | — | — | 1 | 5.08 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL144757 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL89250 | — | IC50 | = | 8400.0 | nM | 5.08 |