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Assay Detail

CHEMBL1009830

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Activity at PPARgamma
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Peroxisome proliferator-activated receptor gamma (CHEMBL235)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of GSK345931A: An EP(1) receptor antagonist with efficacy in preclinical models of inflammatory pain.
Hall A, Brown SH, Budd C, Clayton NM, Giblin GM, Goldsmith P, Hayhow TG, Hurst DN, Naylor A, Anthony Rawlings D, Scoccitti T, Wilson AW, Winchester WJ.
Bioorg Med Chem Lett (2009) 19 : 497 -501
PubMed 19036582 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.40 5.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL467510 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL467510 EC50 = 3981.07 nM 5.40