Assay Detail
Binding
CHEMBL1010052
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Inhibition of MMP13
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Dual inhibitors of matrix metalloproteinases and carbonic anhydrases: iminodiacetyl-based hydroxamate-benzenesulfonamide conjugates.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.63 | 9.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL471537 | — | — | 1 | 9.92 |
| CHEMBL515980 | — | — | 1 | 9.48 |
| CHEMBL472899 | — | — | 1 | 8.80 |
| CHEMBL514138 | CGS-27023A | — | 1 | 8.26 |
| CHEMBL515083 | — | — | 1 | 6.67 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL471537 | — | IC50 | = | 0.12 | nM | 9.92 |
| CHEMBL515980 | — | IC50 | = | 0.33 | nM | 9.48 |
| CHEMBL472899 | — | IC50 | = | 1.6 | nM | 8.80 |
| CHEMBL514138 | CGS-27023A | IC50 | = | 5.5 | nM | 8.26 |
| CHEMBL515083 | — | IC50 | = | 213.0 | nM | 6.67 |