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Assay Detail

CHEMBL1010083

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Agrobacterium sp. beta galactosidase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Agrobacterium sp.
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

1-Deoxygalactonojirimycin-lysine hybrids as potent D-galactosidase inhibitors.
Steiner AJ, Schitter G, Stütz AE, Wrodnigg TM, Tarling CA, Withers SG, Fantur K, Mahuran D, Paschke E, Tropak M.
Bioorg Med Chem (2008) 16 : 10216 -10220
PubMed 18996021 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 7 4.80 5.51

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL461161 1 5.51
CHEMBL505422 1 5.00
CHEMBL454920 1 4.68
CHEMBL110458 MIGALASTAT 4.0 1 4.00
CHEMBL459224 1 -
CHEMBL508985 1 -
CHEMBL446381 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL461161 Ki = 3100.0 nM 5.51
CHEMBL505422 Ki = 10000.0 nM 5.00
CHEMBL454920 Ki = 21000.0 nM 4.68
CHEMBL110458 MIGALASTAT Ki = 100000.0 nM 4.00
CHEMBL459224 Ki = 1900000.0 nM -
CHEMBL508985 Ki = 170000.0 nM -
CHEMBL446381 Ki = 140000.0 nM -