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Assay Detail

CHEMBL1010229

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Physicochemical
Partition coefficient, log P of the compound
6
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Physicochemical
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Iron chelators of the dipyridylketone thiosemicarbazone class: precomplexation and transmetalation effects on anticancer activity.
Bernhardt PV, Sharpe PC, Islam M, Lovejoy DB, Kalinowski DS, Richardson DR.
J Med Chem (2009) 52 : 407 -415
PubMed 19090766 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
LogP 5 - -
IC50 1 5.78 5.78

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL216895 1 5.78
CHEMBL385873 1 -
CHEMBL438288 1 -
CHEMBL413443 1 -
CHEMBL385064 1 -
CHEMBL275925 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL216895 IC50 = 1680.0 nM 5.78
CHEMBL385873 LogP = 0.78 -
CHEMBL438288 LogP = 3.18 -
CHEMBL413443 LogP = 1.23 -
CHEMBL385064 LogP = 2.19 -
CHEMBL275925 LogP = 1.96 -