Assay Detail
Binding
CHEMBL1010560
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HCV NS5B polymerase-mediated RNA synthesis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Hepatitis C virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The design, synthesis, and antiviral activity of monofluoro and difluoro analogues of 4'-azidocytidine against hepatitis C virus replication: the discovery of 4'-azido-2'-deoxy-2'-fluorocytidine and 4'-azido-2'-dideoxy-2',2'-difluorocytidine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.89 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL393857 | 4'-AZIDOCYTIDINE | -1.0 | 1 | 5.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL393857 | 4'-AZIDOCYTIDINE | EC50 | = | 1280.0 | nM | 5.89 |