Assay Detail
Binding
CHEMBL1010812
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Irreversible inhibition of human ODCase
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.35 | 5.96 |
| Kinact | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL474164 | — | — | 2 | 5.96 |
| CHEMBL514166 | — | — | 2 | 4.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL474164 | — | Ki | = | 1100.0 | nM | 5.96 |
| CHEMBL514166 | — | Ki | = | 18200.0 | nM | 4.74 |
| CHEMBL474164 | — | Kinact | = | 158.0 | /hr | - |
| CHEMBL514166 | — | Kinact | = | 41.0 | /hr | - |