Assay Detail
Binding
CHEMBL1011500
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Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plot
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of Trypanosoma brucei glucose-6-phosphate dehydrogenase by human steroids and their effects on the viability of cultured parasites.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 5.37 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272195 | EPIANDROSTERONE | — | 1 | 5.52 |
| CHEMBL90593 | PRASTERONE | 4.0 | 1 | 5.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272195 | EPIANDROSTERONE | Ki | = | 3000.0 | nM | 5.52 |
| CHEMBL90593 | PRASTERONE | Ki | = | 6200.0 | nM | 5.21 |