Assay Detail
Functional
CHEMBL1012566
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Cytotoxicity against human K562 cells after 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | K562 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.53 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL421884 | — | — | 1 | 6.02 |
| CHEMBL516028 | — | — | 1 | 5.94 |
| CHEMBL474774 | — | — | 1 | 5.79 |
| CHEMBL475160 | — | — | 1 | 5.42 |
| CHEMBL472999 | — | — | 1 | 5.04 |
| CHEMBL3216440 | — | — | 1 | 4.94 |
| CHEMBL339586 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL421884 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL516028 | — | IC50 | = | 1160.0 | nM | 5.94 |
| CHEMBL474774 | — | IC50 | = | 1640.0 | nM | 5.79 |
| CHEMBL475160 | — | IC50 | = | 3840.0 | nM | 5.42 |
| CHEMBL472999 | — | IC50 | = | 9080.0 | nM | 5.04 |
| CHEMBL3216440 | — | IC50 | = | 11370.0 | nM | 4.94 |
| CHEMBL339586 | — | IC50 | > | 50000.0 | nM | - |