Assay Detail
Functional
CHEMBL1012568
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Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | B16 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.65 | 6.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL474774 | — | — | 1 | 6.21 |
| CHEMBL516028 | — | — | 1 | 6.16 |
| CHEMBL421884 | — | — | 1 | 5.85 |
| CHEMBL475160 | — | — | 1 | 5.57 |
| CHEMBL472999 | — | — | 1 | 5.27 |
| CHEMBL3216440 | — | — | 1 | 4.86 |
| CHEMBL339586 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL474774 | — | IC50 | = | 620.0 | nM | 6.21 |
| CHEMBL516028 | — | IC50 | = | 690.0 | nM | 6.16 |
| CHEMBL421884 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL475160 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL472999 | — | IC50 | = | 5360.0 | nM | 5.27 |
| CHEMBL3216440 | — | IC50 | = | 13880.0 | nM | 4.86 |
| CHEMBL339586 | — | IC50 | > | 50000.0 | nM | - |