Assay Detail
Binding
CHEMBL1013096
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to rat cloned KA1 receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Glutamate receptor ionotropic, kainate 4 (CHEMBL3044) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.87 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL275040 | KAINIC ACID | 2.0 | 1 | 8.33 |
| CHEMBL482097 | DOMORIC ACID | — | 1 | 7.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL275040 | KAINIC ACID | Ki | = | 4.7 | nM | 8.33 |
| CHEMBL482097 | DOMORIC ACID | Ki | = | 40.0 | nM | 7.40 |