Assay Detail
Functional
CHEMBL1013736
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Agonist activity at human recombinant motilin receptor expressed in CHO cells by FLIPR assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.65 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL501315 | — | — | 1 | 8.00 |
| CHEMBL532 | ERYTHROMYCIN | 4.0 | 1 | 7.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL501315 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL532 | ERYTHROMYCIN | EC50 | = | 50.12 | nM | 7.30 |