Assay Detail
Binding
CHEMBL1013930
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Displacement of [3H]ketanserin from 5HT2 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The role of receptor binding in drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.79 | 9.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL51 | KETANSERIN | 3.0 | 1 | 9.40 |
| CHEMBL263881 | LYSERGIDE | 2.0 | 1 | 8.82 |
| CHEMBL1065 | METHYSERGIDE | 4.0 | 1 | 8.17 |
| CHEMBL8165 | 5-METHOXYTRYPTAMINE | — | 1 | 6.30 |
| CHEMBL39 | SEROTONIN | 3.0 | 1 | 6.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL51 | KETANSERIN | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL263881 | LYSERGIDE | Ki | = | 1.5 | nM | 8.82 |
| CHEMBL1065 | METHYSERGIDE | Ki | = | 6.8 | nM | 8.17 |
| CHEMBL8165 | 5-METHOXYTRYPTAMINE | Ki | = | 500.0 | nM | 6.30 |
| CHEMBL39 | SEROTONIN | Ki | = | 531.0 | nM | 6.28 |