Assay Detail
Binding
CHEMBL1014040
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of xanthine oxidase-mediated formation of uric acid by spectrophotometry
11
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Antioxidant and free-radical scavenging activity of constituents of the leaves of Tachigalia paniculata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.90 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 5.52 |
| CHEMBL451090 | — | — | 1 | 5.21 |
| CHEMBL503182 | — | — | 1 | 5.19 |
| CHEMBL82242 | QUERCITRIN | — | 1 | 4.83 |
| CHEMBL65675 | GALLIC ACID METHYL ESTER | — | 1 | 4.81 |
| CHEMBL250450 | ISOQUERCETIN | 2.0 | 2 | 4.58 |
| CHEMBL486027 | METHYL PROTOCATECHUATE | — | 1 | 4.53 |
| CHEMBL17291 | CAFFEOYL ALDEHYDE | — | 1 | 4.50 |
| CHEMBL275563 | ISOVANILLIN | — | 1 | - |
| CHEMBL325372 | METHYLPARABEN | -1.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL50 | QUERCETIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL451090 | — | IC50 | = | 6130.0 | nM | 5.21 |
| CHEMBL503182 | — | IC50 | = | 6520.0 | nM | 5.19 |
| CHEMBL82242 | QUERCITRIN | IC50 | = | 14740.0 | nM | 4.83 |
| CHEMBL65675 | GALLIC ACID METHYL ESTER | IC50 | = | 15520.0 | nM | 4.81 |
| CHEMBL250450 | ISOQUERCETIN | IC50 | = | 26310.0 | nM | 4.58 |
| CHEMBL486027 | METHYL PROTOCATECHUATE | IC50 | = | 29640.0 | nM | 4.53 |
| CHEMBL17291 | CAFFEOYL ALDEHYDE | IC50 | = | 31500.0 | nM | 4.50 |
| CHEMBL250450 | ISOQUERCETIN | IC50 | > | 50000.0 | nM | - |
| CHEMBL275563 | ISOVANILLIN | IC50 | > | 50000.0 | nM | - |
| CHEMBL325372 | METHYLPARABEN | IC50 | > | 50000.0 | nM | - |