Assay Detail
Binding
CHEMBL1014905
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Inhibition of tubulin assembly
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.28 | 5.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL77552 | CENTAUREIDIN | — | 1 | 5.52 |
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 5.40 |
| CHEMBL18351 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL77552 | CENTAUREIDIN | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL159 | VINBLASTINE | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL18351 | — | IC50 | = | 12000.0 | nM | 4.92 |