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Assay Detail

CHEMBL1015127

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Bel-7402
Confidence 1 — Organism
Curated By Autocuration

Target

Bel-7402 (CHEMBL614279)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents.
Tian ZY, Xie SQ, Du YW, Ma YF, Zhao J, Gao WY, Wang CJ.
Eur J Med Chem (2009) 44 : 393 -399
PubMed 18423800 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.71 5.97

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL474774 1 5.97
CHEMBL516028 1 5.45

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL474774 IC50 = 1060.0 nM 5.97
CHEMBL516028 IC50 = 3560.0 nM 5.45