Assay Detail
Binding
CHEMBL1015152
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Crotalus adamanteus venom PLA2 assessed as effect on 1-hexadecanoyl-2-(1-pyrenedecanoyl)-sn-glycero-3-phosphoglycerol hydrolysis at 0.15 uM
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Crotalus adamanteus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Molecular modeling and inhibition of phospholipase A2 by polyhydroxy phenolic compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.83 | 8.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473159 | PHLOROGLUCINOL | 3.0 | 1 | 8.06 |
| CHEMBL452477 | 2,4,6-TRIHYDROXYACETOPHENONE | — | 1 | 8.05 |
| CHEMBL24147 | RESORCINOL | -1.0 | 1 | 8.05 |
| CHEMBL454739 | — | — | 1 | 7.52 |
| CHEMBL243374 | — | — | 1 | 7.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473159 | PHLOROGLUCINOL | Ki | = | 8.77 | nM | 8.06 |
| CHEMBL452477 | 2,4,6-TRIHYDROXYACETOPHENONE | Ki | = | 8.9 | nM | 8.05 |
| CHEMBL24147 | RESORCINOL | Ki | = | 8.83 | nM | 8.05 |
| CHEMBL454739 | — | Ki | = | 30.11 | nM | 7.52 |
| CHEMBL243374 | — | Ki | = | 33.31 | nM | 7.48 |