Assay Detail
ADMET
CHEMBL1015618
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Cytotoxicity against african green monkey Vero cells assessed as inhibition of colony formation after 5 to 8 days by colony assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Chlorocebus sabaeus |
| Cell Type | Vero |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationship study of lamellarin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.66 | 7.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL373114 | LAMELLARIN D | — | 1 | 7.98 |
| CHEMBL517954 | — | — | 1 | 5.33 |
| CHEMBL105 | MITOMYCIN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL373114 | LAMELLARIN D | IC50 | = | 10.5 | nM | 7.98 |
| CHEMBL517954 | — | IC50 | = | 4700.0 | nM | 5.33 |
| CHEMBL105 | MITOMYCIN | IC50 | - | — | - |