Assay Detail

CHEMBL1015622

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Functional

Immunomodulatory activity in PHA-stimulated human PBMC assessed as inhibition of IL2 production after 3 days by enzyme immuno assay

ChEMBL ↗

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Target

PBMC (CHEMBL613107) ↗

Open DB target context

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Primary target PBMC

CHEMBL613107

Anchored from Assay target.

Protein identity PBMC

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	PBMC
Confidence	1 — Organism
Curated By	Autocuration

Target

PBMC (CHEMBL613107) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Immunomodulatory proanthocyanidins from Ecdysanthera utilis.

Lin LC, Kuo YC, Chou CJ.
J Nat Prod (2002) 65 : 505 -508
PubMed 11975489 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	4.60	4.60
Activity	1	-	-

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL450916	PROANTHOCYANIDIN A1	—	2	4.60

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL450916	PROANTHOCYANIDIN A1	IC50	=	25000.0	nM	4.60
CHEMBL450916	PROANTHOCYANIDIN A1	Activity		-	—	-