Assay Detail
ADMET
CHEMBL1016233
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Cytotoxicity against human H9 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Development and preclinical studies of broad-spectrum anti-HIV agent (3'R,4'R)-3-cyanomethyl-4-methyl-3',4'-di-O-(S)-camphanoyl-(+)-cis-khellactone (3-cyanomethyl-4-methyl-DCK).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.62 | 4.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506407 | — | — | 1 | 4.63 |
| CHEMBL423448 | — | — | 1 | 4.60 |
| CHEMBL456945 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506407 | — | IC50 | = | 23600.0 | nM | 4.63 |
| CHEMBL423448 | — | IC50 | = | 24900.0 | nM | 4.60 |
| CHEMBL456945 | — | IC50 | > | 37000.0 | nM | - |