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Assay Detail

CHEMBL1016598

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]WIN-from cocaine site of dopamine transporter
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Sodium-dependent dopamine transporter (CHEMBL238)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

The role of receptor binding in drug discovery.
Sweetnam PM, Caldwell L, Lancaster J, Bauer C, McMillan B, Kinnier WJ, Price CH.
J Nat Prod (1993) 56 : 441 -455
PubMed 8496700 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.63 7.63

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL273575 NOMIFENSINE 4.0 1 7.63

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL273575 NOMIFENSINE Ki = 23.5 nM 7.63