Assay Detail
Binding
CHEMBL1016695
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Displacement of [3H]colchicine from tubulin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Novel carbazole and acyl-indole antimitotics.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.62 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL466673 | — | — | 1 | 5.79 |
| CHEMBL312862 | DEMECOLCINE | 2.0 | 1 | 5.45 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL466673 | — | IC50 | = | 1610.0 | nM | 5.79 |
| CHEMBL312862 | DEMECOLCINE | IC50 | = | 3580.0 | nM | 5.45 |