Assay Detail
Binding
CHEMBL1017181
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I-Tyr4]BN form BB2 receptor in human PC3 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural assessment and biological evaluation of two N3S bombesin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.99 | 9.23 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2372319 | — | — | 1 | 9.23 |
| CHEMBL525820 | — | — | 1 | 8.91 |
| CHEMBL2372320 | — | — | 1 | 8.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2372319 | — | IC50 | = | 0.59 | nM | 9.23 |
| CHEMBL525820 | — | IC50 | = | 1.24 | nM | 8.91 |
| CHEMBL2372320 | — | IC50 | = | 1.45 | nM | 8.84 |