Assay Detail
Functional
CHEMBL1018193
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of 12-hydroxy-5,8,10,14-eicosatetraenoic acid formation in Wistar King platelets
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Effects of phenolic constituents from the mulberry tree on arachidonate metabolism in rat platelets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.05 | 4.05 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL445265 | MULBERROFURAN G | — | 1 | 4.05 |
| CHEMBL505416 | MULBERROFURAN J | — | 1 | - |
| CHEMBL455619 | MULBERROSIDE A | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL445265 | MULBERROFURAN G | IC50 | = | 89000.0 | nM | 4.05 |
| CHEMBL505416 | MULBERROFURAN J | IC50 | = | 823000.0 | nM | - |
| CHEMBL455619 | MULBERROSIDE A | Activity | - | — | - |