Assay Detail
Functional
CHEMBL1018199
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Inhibition of thromboxane B2 formation in Wistar King platelets
8
Total Activities
8
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Cell Type | Platelet |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Effects of phenolic constituents from the mulberry tree on arachidonate metabolism in rat platelets.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.30 | 4.46 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL445265 | MULBERROFURAN G | — | 1 | 4.46 |
| CHEMBL464610 | SANGGENON D | — | 1 | 4.32 |
| CHEMBL505416 | MULBERROFURAN J | — | 1 | 4.29 |
| CHEMBL506234 | KUMANON H | — | 1 | 4.12 |
| CHEMBL444942 | KUMANON G | — | 1 | - |
| CHEMBL455619 | MULBERROSIDE A | — | 1 | - |
| CHEMBL447615 | MULBERROFURAN Q | — | 1 | - |
| CHEMBL204813 | SANGGENON C | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL445265 | MULBERROFURAN G | IC50 | = | 34700.0 | nM | 4.46 |
| CHEMBL464610 | SANGGENON D | IC50 | = | 48300.0 | nM | 4.32 |
| CHEMBL505416 | MULBERROFURAN J | IC50 | = | 50700.0 | nM | 4.29 |
| CHEMBL506234 | KUMANON H | IC50 | = | 75700.0 | nM | 4.12 |
| CHEMBL444942 | KUMANON G | IC50 | = | 132000.0 | nM | - |
| CHEMBL455619 | MULBERROSIDE A | Activity | - | — | - | |
| CHEMBL447615 | MULBERROFURAN Q | IC50 | = | 355000.0 | nM | - |
| CHEMBL204813 | SANGGENON C | IC50 | = | 180000.0 | nM | - |