Assay Detail

CHEMBL1018920

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Binding

Inhibition of calmodulin-stimulated Ca2+/Mg2+ ATPase activity in human erythrocyte membrane

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Bisbenzylisoquinoline alkaloids.

Schiff PL.
J Nat Prod (1991) 54 : 645 -749
PubMed 1955879 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	5.34	6.46

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL454806	—	—	1	6.46
CHEMBL504323	BERBAMINE	—	1	4.22

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL454806	—	IC50	=	350.0	nM	6.46
CHEMBL504323	BERBAMINE	IC50	=	60000.0	nM	4.22