Assay Detail
Binding
CHEMBL1019374
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of bovine brain PI-PLCgamma1 at 125 ug/mL
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (CHEMBL5566) ↗| Type | SINGLE PROTEIN |
| Organism | Bos taurus |
Publication
Phospholipase Cgamma1 inhibitory principles from the sarcotestas of Ginkgo biloba.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.30 | 5.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL470263 | — | — | 1 | 5.46 |
| CHEMBL470768 | GINKGOLIC ACID 17:1 | — | 1 | 4.13 |
| CHEMBL445177 | GINGKOLIC ACID | — | 1 | 4.12 |
| CHEMBL448270 | — | — | 1 | 4.06 |
| CHEMBL34689 | — | — | 1 | 4.03 |
| CHEMBL470127 | — | — | 1 | 4.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL470263 | — | IC50 | = | 3510.0 | nM | 5.46 |
| CHEMBL470768 | GINKGOLIC ACID 17:1 | IC50 | = | 74020.0 | nM | 4.13 |
| CHEMBL445177 | GINGKOLIC ACID | IC50 | = | 76320.0 | nM | 4.12 |
| CHEMBL448270 | — | IC50 | = | 87950.0 | nM | 4.06 |
| CHEMBL34689 | — | IC50 | = | 92580.0 | nM | 4.03 |
| CHEMBL470127 | — | IC50 | = | 95020.0 | nM | 4.02 |