Assay Detail
Binding
CHEMBL1019442
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant 15-lipoxygenase b
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design and synthesis of 4-methoxyphenylacetic acid esters as 15-lipoxygenase inhibitors and SAR comparative studies of them.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.57 | 4.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473974 | — | — | 1 | 4.93 |
| CHEMBL473379 | — | — | 1 | 4.20 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473974 | — | IC50 | = | 11700.0 | nM | 4.93 |
| CHEMBL473379 | — | IC50 | = | 63200.0 | nM | 4.20 |