Assay Detail
Functional
CHEMBL1019482
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at Escherichia coli DH5alpha LasR receptor by beta-galctosidase reporter gene assay
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 11 | 6.22 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL503197 | — | — | 1 | 8.00 |
| CHEMBL467396 | — | — | 1 | 5.47 |
| CHEMBL515217 | — | — | 1 | 5.20 |
| CHEMBL405298 | — | — | 1 | - |
| CHEMBL459085 | — | — | 1 | - |
| CHEMBL458227 | — | — | 1 | - |
| CHEMBL467397 | — | — | 1 | - |
| CHEMBL499747 | — | — | 1 | - |
| CHEMBL463321 | — | — | 1 | - |
| CHEMBL8483 | — | — | 1 | - |
| CHEMBL458201 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL503197 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL467396 | — | EC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL515217 | — | EC50 | = | 6300.0 | nM | 5.20 |
| CHEMBL405298 | — | EC50 | - | — | - | |
| CHEMBL459085 | — | EC50 | - | — | - | |
| CHEMBL458227 | — | EC50 | - | — | - | |
| CHEMBL467397 | — | EC50 | - | — | - | |
| CHEMBL499747 | — | EC50 | - | — | - | |
| CHEMBL463321 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL8483 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL458201 | — | EC50 | > | 10000.0 | nM | - |