Assay Detail
Binding
CHEMBL1019882
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Displacement of [3H]Naltrindole form delta opioid receptor in guinea pig brain
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 10 | 7.62 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL517166 | — | — | 1 | 8.70 |
| CHEMBL55033 | — | — | 1 | 8.47 |
| CHEMBL2367604 | — | — | 1 | 8.44 |
| CHEMBL461229 | — | — | 1 | 8.01 |
| CHEMBL2107292 | KETAZOCINE | 2.0 | 1 | 7.70 |
| CHEMBL511691 | — | — | 1 | 7.70 |
| CHEMBL459746 | — | — | 1 | 7.47 |
| CHEMBL464071 | — | — | 1 | 7.17 |
| CHEMBL70 | MORPHINE | 4.0 | 1 | 6.85 |
| CHEMBL505011 | — | — | 1 | 5.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL517166 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL55033 | — | Ki | = | 3.4 | nM | 8.47 |
| CHEMBL2367604 | — | Ki | = | 3.6 | nM | 8.44 |
| CHEMBL461229 | — | Ki | = | 9.8 | nM | 8.01 |
| CHEMBL2107292 | KETAZOCINE | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL511691 | — | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL459746 | — | Ki | = | 34.0 | nM | 7.47 |
| CHEMBL464071 | — | Ki | = | 67.0 | nM | 7.17 |
| CHEMBL70 | MORPHINE | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL505011 | — | Ki | = | 1900.0 | nM | 5.72 |