Assay Detail
Binding
CHEMBL1020150
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Inhibition of Rous sarcoma virus v-Src
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rous sarcoma virus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibitors of protein tyrosine kinase pp60v-src: sterol sulfates from the brittle star Ophiarachna incrassata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.98 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL512187 | HELENAQUINOL | — | 1 | 6.22 |
| CHEMBL513747 | HELENAQUINONE | — | 1 | 5.82 |
| CHEMBL500050 | — | — | 1 | 4.96 |
| CHEMBL444771 | — | — | 1 | 4.92 |
| CHEMBL503723 | — | — | 1 | 4.51 |
| CHEMBL455235 | — | — | 1 | 4.21 |
| CHEMBL503339 | — | — | 1 | 4.19 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL512187 | HELENAQUINOL | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL513747 | HELENAQUINONE | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL500050 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL444771 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL503723 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL455235 | — | IC50 | = | 62000.0 | nM | 4.21 |
| CHEMBL503339 | — | IC50 | = | 65000.0 | nM | 4.19 |