Assay Detail
Binding
CHEMBL1020944
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Inhibition of rat liver mitochondrial ATPase assessed per mg of protein
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Inhibition of mitochondrial NADH oxidase, succinoxidase, and ATPase by naturally occurring flavonoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.42 | 6.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28626 | MORIN | — | 1 | 6.92 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 6.69 |
| CHEMBL164 | MYRICETIN | — | 1 | 6.43 |
| CHEMBL31574 | FISETIN | 2.0 | 1 | 6.32 |
| CHEMBL9352 | NARINGENIN | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28626 | MORIN | IC50 | = | 120.0 | nM | 6.92 |
| CHEMBL50 | QUERCETIN | IC50 | = | 205.0 | nM | 6.69 |
| CHEMBL164 | MYRICETIN | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL31574 | FISETIN | IC50 | = | 480.0 | nM | 6.32 |
| CHEMBL9352 | NARINGENIN | IC50 | = | 1800.0 | nM | 5.75 |