Assay Detail
Functional
CHEMBL1021187
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Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The novel phosphoramidate derivatives of NSAID 3-hydroxypropylamides: synthesis, cytostatic and antiviral activity evaluations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.79 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL506356 | — | — | 1 | 5.05 |
| CHEMBL460116 | — | — | 1 | 4.92 |
| CHEMBL463071 | — | — | 1 | 4.85 |
| CHEMBL460327 | — | — | 1 | 4.85 |
| CHEMBL455791 | — | — | 1 | 4.80 |
| CHEMBL25725 | — | — | 1 | 4.66 |
| CHEMBL460110 | — | — | 1 | 4.41 |
| CHEMBL474168 | — | — | 1 | - |
| CHEMBL474169 | — | — | 1 | - |
| CHEMBL468947 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL506356 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL460116 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL463071 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL460327 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL455791 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL25725 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL460110 | — | IC50 | = | 39000.0 | nM | 4.41 |
| CHEMBL474168 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL474169 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL468947 | — | IC50 | > | 100000.0 | nM | - |