Assay Detail
Binding
CHEMBL1021534
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]DAMGO from CCK2R-MOPR coexpressed in CHO cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Gastrin/cholecystokinin type B receptor (CHEMBL298) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Induced association of mu opioid (MOP) and type 2 cholecystokinin (CCK2) receptors by novel bivalent ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 8.42 | 10.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL452991 | — | — | 1 | 10.39 |
| CHEMBL501238 | — | — | 1 | 8.41 |
| CHEMBL509792 | — | — | 1 | 8.14 |
| CHEMBL38874 | DAMGO | — | 1 | 7.96 |
| CHEMBL442943 | — | — | 1 | 7.85 |
| CHEMBL502398 | — | — | 1 | 7.79 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL452991 | — | Ki | = | 0.0407 | nM | 10.39 |
| CHEMBL501238 | — | Ki | = | 3.9 | nM | 8.41 |
| CHEMBL509792 | — | Ki | = | 7.3 | nM | 8.14 |
| CHEMBL38874 | DAMGO | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL442943 | — | Ki | = | 14.2 | nM | 7.85 |
| CHEMBL502398 | — | Ki | = | 16.3 | nM | 7.79 |