Assay Detail
Binding
CHEMBL1022248
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Reversible inhibition of human ODCase
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 5.08 | 6.46 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL473587 | — | — | 1 | 6.46 |
| CHEMBL474165 | — | — | 1 | 4.78 |
| CHEMBL474163 | — | — | 1 | 4.01 |
| CHEMBL512577 | — | — | 1 | - |
| CHEMBL472783 | — | — | 1 | - |
| CHEMBL514137 | — | — | 1 | - |
| CHEMBL463623 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL473587 | — | Ki | = | 350.0 | nM | 6.46 |
| CHEMBL474165 | — | Ki | = | 16600.0 | nM | 4.78 |
| CHEMBL474163 | — | Ki | = | 98000.0 | nM | 4.01 |
| CHEMBL512577 | — | Ki | - | — | - | |
| CHEMBL472783 | — | Ki | - | — | - | |
| CHEMBL514137 | — | Ki | - | — | - | |
| CHEMBL463623 | — | Ki | - | — | - |